Research

Tumor-State Explorer

A transparent, rule-based, nine-axis profile — with explainability and a missing-data list.

Tumor-State Explorer turns the structured record into a rule-based profile across nine axes of tumor behavior. It is not ML, not a prediction model, and not a recommender. The rules are visible in source (services/tumor_state.py) and each output has an explainability section.

The nine axes

  • Driver signaling
  • Immune evasion
  • Hypoxia / microenvironment stress
  • Metabolic plasticity
  • DNA-repair escape
  • Death resistance
  • Dormancy / MRD risk
  • Metastatic behavior
  • Treatment resistance

Per-axis outputs

  • A score and level (e.g. low / moderate / high).
  • Reasons — the inputs that drove the score, by name.
  • Missing data — the inputs that would change the score if known.
  • Uncertainty — a combined score of how much the answer rests on assumptions.
  • Public-dataset references — pointers into the Data Bank when relevant.

Safety

Cautious language only — 'may be associated with', 'requires validation'. The Explorer is for research and hypothesis generation; it is not a clinical decision tool.